2016年2月1日月曜日

Unit12: Smoking and Alcohol

Reading 1: WHO - Facts about smoking. 
 Key facts - Tobacco kills up to half of its users. - Tobacco kills around 6 million people each year. More than 5 million of those deaths are the result of direct tobacco use while more than 600 000 are the result of non-smokers being exposed to second-hand smoke. - Nearly 80% of the world's 1 billion smokers live in low- and middle-income countries. Leading cause of death, illness and impoverishment The tobacco epidemic is one of the biggest public health threats the world has ever faced, killing around 6 million people a year. More than 5 million of those deaths are the result of direct tobacco use while more than 600 000 are the result of non-smokers being exposed to second-hand smoke. Nearly 80% of the more than 1 billion smokers worldwide live in low- and middle-income countries, where the burden of tobacco-related illness and death is heaviest. Tobacco users who die prematurely deprive their families of income, raise the cost of health care and hinder economic development. In some countries, children from poor households are frequently employed in tobacco farming to provide family income. These children are especially vulnerable to "green tobacco sickness", which is caused by the nicotine that is absorbed through the skin from the handling of wet tobacco leaves. Surveillance is key Good monitoring tracks the extent and character of the tobacco epidemic and indicates how best to tailor policies. Only 1 in 3 countries, representing one third of the world's population, monitors tobacco use by repeating nationally representative youth and adult surveys at least once every 5 years. Second-hand smoke kills Second-hand smoke is the smoke that fills restaurants, offices or other enclosed spaces when people burn tobacco products such as cigarettes, bidis and water-pipes. There are more than 4000 chemicals in tobacco smoke, of which at least 250 are known to be harmful and more than 50 are known to cause cancer. There is no safe level of exposure to second-hand tobacco smoke. - In adults, second-hand smoke causes serious cardiovascular and respiratory diseases, including coronary heart disease and lung cancer. In infants, it causes sudden death. In pregnant women, it causes low birth weight. - Almost half of children regularly breathe air polluted by tobacco smoke in public places. - Second-hand smoke causes more than 600 000 premature deaths per year. - In 2004, children accounted for 28% of the deaths attributable to second-hand smoke. Every person should be able to breathe tobacco-smoke-free air. Smoke-free laws protect the health of non-smokers, are popular, do not harm business and encourage smokers to quit. Over 1.3 billion people, or 18% of the world's population, are protected by comprehensive national smoke-free laws. Tobacco users need help to quit Studies show that few people understand the specific health risks of tobacco use. For example, a 2009 survey in China revealed that only 38% of smokers knew that smoking causes coronary heart disease and only 27% knew that it causes stroke. Among smokers who are aware of the dangers of tobacco, most want to quit. Counselling and medication can more than double the chance that a smoker who tries to quit will succeed. National comprehensive cessation services with full or partial cost-coverage are available to assist tobacco users to quit in only 24 countries, representing 15% of the world's population. There is no cessation assistance of any kind in one quarter of low-income countries. Picture warnings work Hard-hitting anti-tobacco advertisements and graphic pack warnings – especially those that include pictures – reduce the number of children who begin smoking and increase the number of smokers who quit. Graphic warnings can persuade smokers to protect the health of non-smokers by smoking less inside the home and avoiding smoking near children. Studies carried out after the implementation of pictorial package warnings in Brazil, Canada, Singapore and Thailand consistently show that pictorial warnings significantly increase people's awareness of the harms of tobacco use. Only 42 countries, representing 19% of the world's population, meet the best practice for pictorial warnings, which includes the warnings in the local language and cover an average of at least half of the front and back of cigarette packs. Most of these countries are low- or middle-income countries. Mass media campaigns can also reduce tobacco consumption by influencing people to protect non-smokers and convincing youths to stop using tobacco. Over half of the world's population live in the 39 countries that have aired at least 1 strong anti-tobacco mass media campaign within the last 2 years. Ad bans lower consumption Bans on tobacco advertising, promotion and sponsorship can reduce tobacco consumption. -A comprehensive ban on all tobacco advertising, promotion and sponsorship could decrease tobacco consumption by an average of about 7%, with some countries experiencing a decline in consumption of up to 16%. -Only 29 countries, representing 12% of the world’s population, have completely banned all forms of tobacco advertising, promotion and sponsorship. -Around 1 country in 3 has minimal or no restrictions at all on tobacco advertising, promotion and sponsorship. Taxes discourage tobacco use Tobacco taxes are the most cost-effective way to reduce tobacco use, especially among young and poor people. A tax increase that increases tobacco prices by 10% decreases tobacco consumption by about 4% in high-income countries and about 5% in low- and middle-income countries. Even so, high tobacco taxes is a measure that is rarely implemented. Only 33 countries, with 10% of the world's population, have introduced taxes on tobacco products so that more than 75% of the retail price is tax. Tobacco tax revenues are on average 269 times higher than spending on tobacco control, based on available data. Illicit trade of tobacco products must be stopped The illicit trade in tobacco products poses major health, economic and security concerns around the world. It is estimated that 1 in every 10 cigarettes and tobacco products consumed globally is illicit. The illicit market is supported by various players, ranging from petty peddlers to organized criminal networks involved in arms and human trafficking. Eliminating illicit trade in tobacco will reduce the harmful consumption of tobacco by restricting availability of cheap, unregulated alternatives and increasing overall tobacco prices. Critically, this will reduce premature deaths from tobacco use and raise tax revenue for governments. Stopping illicit trade in tobacco products is a health priority, and is achievable. But to do so requires improvement of national and sub-national tax administration systems and international collaboration, such as ratification and implementation of the Protocol to Eliminate the Illicit Trade in Tobacco Products, an international treaty in its own right, negotiated by parties to the WHO Framework Convention on Tobacco Control (WHO FCTC). While publicly stating its support for action against the illicit trade, the tobacco industry’s behind-the-scenes behaviour has been very different. Internal industry documents released as a result of court cases demonstrate that the tobacco industry has actively fostered the illicit trade globally. It also works to block implementation of tobacco control measures, such as tax increases and pictorial health warnings, by misleadingly arguing they will fuel the illicit trade. WHO response WHO is committed to fighting the global tobacco epidemic. The WHO Framework Convention on Tobacco Control entered into force in February 2005. Since then, it has become one of the most widely embraced treaties in the history of the United Nations with 180 Parties covering 90% of the world's population. The WHO Framework Convention is WHO's most important tobacco control tool and a milestone in the promotion of public health. It is an evidence-based treaty that reaffirms the right of people to the highest standard of health, provides legal dimensions for international health cooperation and sets high standards for compliance. In 2008, WHO introduced a practical, cost-effective way to scale up implementation of provisions of the WHO Framework Convention on the ground: MPOWER. Each MPOWER measure corresponds to at least 1 provision of the WHO Framework Convention on Tobacco Control. The 6 MPOWER measures are: - Monitor tobacco use and prevention policies - Protect people from tobacco use - Offer help to quit tobacco use - Warn about the dangers of tobacco - Enforce bans on tobacco advertising, promotion and sponsorship - Raise taxes on tobacco. For more details on progress made for tobacco control at global, regional and country level, please refer to the series of WHO reports on the global tobacco epidemic. The WHO FCTC Protocol to Eliminate the Illicit Trade in Tobacco Products requires a wide range of measures relating to the tobacco supply chain, including the licensing of imports, exports and manufacture of tobacco products; the establishment of tracking and tracing systems and the imposition of penal sanctions on those responsible for illicit trade. It would also criminalize illicit production and cross-border smuggling. 

 Reading 2: WHO World No Tobacco Day
New release 28 MAY 2015 GENEVA - Eliminating the illicit trade in tobacco would generate an annual tax windfall of US$ 31 billion for governments, improve public health, help cut crime and curb an important revenue source for the tobacco industry. Those are the key themes of World No Tobacco Day on 31 May when WHO will urge Member States to sign the "Protocol to Eliminate the Illicit Trade in Tobacco Products". “The Protocol offers the world a unique legal instrument to counter and eventually eliminate a sophisticated criminal activity,” says Dr Margaret Chan, WHO Director-General. “Fully implemented, it will replenish government revenues and allow more spending on health.” So far, 8 countries have ratified the Protocol, short of the target of 40 needed for it to become international law. Once that happens, the Protocol’s provisions on securing the supply chain, enhanced international cooperation and other safeguards will come into force. The Protocol is an international treaty in its own right negotiated by parties to the WHO Framework Convention on Tobacco Control (WHO FCTC), which has been ratified by 180 Parties. Article 15 commits signatories to eliminate all forms of illicit trade in tobacco products. The Protocol requires a wide range of measures relating to the tobacco supply chain, including the licensing of imports, exports and manufacture of tobacco products; the establishment of tracking and tracing systems and the imposition of penal sanctions on those responsible for illicit trade. It would also criminalise illicit production and cross border smuggling. “The Protocol faces overt and covert resistance from the tobacco industry,” says Dr Vera da Costa e Silva, Head of the WHO FCTC Secretariat. “Manufacturers know that once implemented, it will become much harder to hook young people and the poor into tobacco addiction.” The illicit tobacco trade offers products at lower prices, primarily by avoiding government taxes through smuggling, illegal manufacturing and counterfeiting. Cheaper tobacco encourages younger tobacco users (who generally have lower incomes) and cuts government revenues, reducing the resources available for socioeconomic development, especially in low-income countries that depend heavily on consumption taxes. This money might otherwise be spent on the provision of public services, including health care. While publicly stating its support for action against the illicit trade, the tobacco industry’s behind-the-scenes behaviour has been very different. Internal industry documents released as a result of court cases demonstrate that the tobacco industry has actively fostered the illicit trade globally. It also works to block implementation of tobacco control measures, like tax increases and pictorial health warnings, by arguing they will fuel the illicit trade. “Public health is engaged in a pitched battle against a ruthless industry,” says Dr Douglas Bettcher, Director of the WHO’s Department for the Prevention of Noncommunicable Diseases. “On this World No Tobacco Day, WHO and its partners are showing the ends that the tobacco industry goes to in the search for profits, including on the black market, and by ensnaring new targets, including young children, to expand its deadly trade.” Policy makers should recognize that the illicit tobacco trade exacerbates the global health epidemic and has serious security implications. Ratification of the Protocol to Eliminate the Illicit Trade in Tobacco Products is a necessary step to combat these twin evils. Editor’s note Tobacco-related illness is one of the biggest public health threats the world has ever faced. Approximately one person dies from a tobacco-linked disease every six seconds, equivalent to almost 6 million people a year. That’s forecast to rise to more than 8 million people a year by 2030, with more than 80% of these preventable deaths occurring among people living in low-and middle-income countries. The WHO Framework Convention for Tobacco Control (WHO FCTC) entered into force in 2005. Parties are obliged over time to take a number of steps to reduce demand and supply for tobacco products including: protecting people from exposure to tobacco smoke, counteracting illicit trade, banning advertising, promotion and sponsorship, banning sales to minors, putting large health warnings on packages of tobacco, increasing tobacco taxes and creating a national coordinating mechanism for tobacco control. There are 180 Parties to the Convention. 

  Reading 3: WHO Global status report on alcohol and health 2014.
 Global status report on alcohol and health 2014 The Global status report on alcohol and health 2014 presents a comprehensive perspective on the global, regional and country consumption of alcohol, patterns of drinking, health consequences and policy responses in Member States. It represents a continuing effort by the World Health Organization (WHO) to support Member States in collecting information in order to assist them in their efforts to reduce the harmful use of alcohol, and its health and social consequences. The report was launched in Geneva on Monday 12 May 2014 during the second meeting of the global network of WHO national counterparts for implementation of the global strategy to reduce the harmful use of alcohol. The report provides a global overview of alcohol consumption in relation to public health (Chapter 1) as well as information on: the consumption of alcohol in populations (Chapter 2); the health consequences of alcohol consumption (Chapter 3); and policy responses at national level (Chapter 4). In addition the report contains country profiles for WHO Member States and appendices with statistical annexes, a description of the data sources and methods used as well as references. 

 Reading 4: WHO reports on alcohol consumption. 
 WHO calls on governments to do more to prevent alcohol-related deaths and diseases News release 12 May 2014 GENEVA - Worldwide, 3.3 million deaths in 2012 were due to harmful use of alcohol, says a new report launched by WHO today. Alcohol consumption can not only lead to dependence but also increases people’s risk of developing more than 200 diseases including liver cirrhosis and some cancers. In addition, harmful drinking can lead to violence and injuries. The report also finds that harmful use of alcohol makes people more susceptible to infectious diseases such as tuberculosis and pneumonia. The "Global status report on alcohol and health 2014" provides country profiles for alcohol consumption in the 194 WHO Member States, the impact on public health and policy responses. “More needs to be done to protect populations from the negative health consequences of alcohol consumption,” says Dr Oleg Chestnov, WHO Assistant Director-General for Noncommunicable Diseases and Mental Health. “The report clearly shows that there is no room for complacency when it comes to reducing the harmful use of alcohol.” Some countries are already strengthening measures to protect people. These include increasing taxes on alcohol, limiting the availability of alcohol by raising the age limit, and regulating the marketing of alcoholic beverages. Report highlights The report also highlights the need for action by countries including: - national leadership to develop policies to reduce harmful use of alcohol (66 WHO Member States had written national alcohol policies in 2012); - national awareness-raising activities (nearly 140 countries reported at least one such activity in the past three years); - health services to deliver prevention and treatment services, in particular increasing prevention, treatment and care for patients and their families, and supporting initiatives for screening and brief interventions. In addition the report shows the need for communities to be engaged in reducing harmful use of alcohol. On average every person in the world aged 15 years or older drinks 6.2 litres of pure alcohol per year. But as less than half the population (38.3%) actually drinks alcohol, this means that those who do drink consume on average 17 litres of pure alcohol annually. The report also points to the fact that a higher percentage of deaths among men than among women are from alcohol-related causes - 7.6% of men’s deaths and 4% of women’s deaths – though there is evidence that women may be more vulnerable to some alcohol-related health conditions compared to men. In addition, the authors note that there is concern over the steady increase in alcohol use among women. “We found that worldwide about 16% of drinkers engage in heavy episodic drinking - often referred to as ‘binge-drinking’ - which is the most harmful to health,” explains Dr Shekhar Saxena, Director for Mental Health and Substance Abuse at WHO. "Lower-income groups are more affected by the social and health consequences of alcohol. They often lack quality health care and are less protected by functional family or community networks.” Globally, Europe is the region with the highest consumption of alcohol per capita, with some of its countries having particularly high consumption rates. Trend analysis shows that the consumption level is stable over the last 5 years in the region, as well as in Africa and the Americas, though increases have been reported in the South-East Asia and the Western Pacific regions. Through a global network, WHO is supporting countries in their development and implementation of policies to reduce the harmful use of alcohol. The need for intensified action was endorsed in the landmark 2011 United Nations General Assembly meeting, which identified alcohol as one of four common risk factors* contributing to the non-communicable diseases (NCDs) epidemic. *The rise of NCDs has been driven by primarily four major risk factors: tobacco use, physical inactivity, the harmful use of alcohol and unhealthy diets (“Noncommunicable diseases and their risk factors” in Programmes, WHO home page). 

Unit11:Cancer

 Reading 1: WHO - Facts about cancer. 
 Cancer is the uncontrolled growth of cells, which can invade and spread to distant sites of the body. Cancer can have severe health consequences, and is a leading cause of death. Lung, prostate, colorectal, stomach, and liver cancer are the most common types of cancer in men, while breast, colorectal, lung, uterine cervix, and stomach cancer are the most common among women. More than 30% of cancer deaths could be prevented by modifying or avoiding key risk factors, especially tobacco use. Early detection, accurate diagnosis, and effective treatment, including pain relief and palliative care, help increase cancer survival rates and reduce suffering. Treatment options include surgery, chemotherapy and radiotherapy, tailored to tumour stage, type and available resources. Comprehensive cancer control plans are needed to improve cancer prevention and care, especially in low-income and middle-income countries. - 8.2 million people die each year from cancer, an estimated 13% of all deaths worldwide. - 70% the increase in new cases of cancer expected over the next 2 decades. - More than 100 cancer types exist, each requiring unique diagnosis and treatment. About the Cancer Control Programme The key mission of WHO Cancer Control Programme is to promote national cancer control policies plans and programmes, integrated to noncommunicable diseases and other related problems. Our core functions are to set norms and standards, promote surveillance, encourage evidence based prevention, early detection, treatment and palliative tailored to the different socioeconomic settings. What is cancer? Cancer is a generic term for a large group of diseases that can affect any part of the body. Other terms used are malignant tumours and neoplasms. One defining feature of cancer is the rapid creation of abnormal cells that grow beyond their usual boundaries, and which can then invade adjoining parts of the body and spread to other organs. This process is referred to as metastasis. Metastases are the major cause of death from cancer. 

 Reading 2: Cancer Research UK - World’s largest independent cancer research and awareness & fund raising charity body 
 Our organisation A number of bodies work together to ensure that we make the best use of the funds we receive and continue to carry out world-class research. Our Trustees The Council of trustees sets the Charity’s strategic direction, monitors the delivery of the Charity’s objectives, uphold its values and governance and advises the Chief Executive. Chief Executive and Executive Board Our Chief Executive and Executive Board work together to ensure that the charity continues to carry out world class research. Annual review 2015 Our Annual Review 2014/15 is packed with highlights of our work across the UK and the inspiring stories of people who have benefited from it. Our Members Cancer Research UK’s constitution provides for the appointment of 100 Members of the charity which are similar to shareholders of a company. Our strategy to beat cancer sooner Our vision is to bring forward the day when all cancers are cured. Our new strategy will give us the foundations we need to tackle the challenges ahead. Our Scientific Executive Board The role of the Scientific Executive Board is to develop and implement Cancer Research UK's scientific strategy. 

 Reading 3: Cancer Research UK - from Wikipedia, the free encyclopedia. 
 Cancer Research UK is a cancer research and awareness charity in the United Kingdom, formed on 4 February 2002 by the merger of The Cancer Research Campaign and the Imperial Cancer Research Fund.Its aim is to reduce the number of deaths from cancer. As the world's largest independent cancer research charity it conducts research into the prevention, diagnosis and treatment of the disease. Research activities are carried out in institutes, universities and hospitals across the UK, both by the charity's own employees and by its grant-funded researchers. It also provides information about cancer and runs campaigns aimed at raising awareness of the disease and influencing public policy. Cancer Research UK's work is almost entirely funded by the public. It raises money through donations, legacies, community fundraising, events, retail and corporate partnerships. Over 40,000 people are regular volunteers. On 18 July 2012 it was announced that Cancer Research UK was to receive its largest ever single donation of £10 million from an anonymous donor. The money will go towards the £100 million funding needed for the Francis Crick Institute in London, the largest biomedical research building in Europe.

 Reading 4: Can cancer be prevented? - A lifestyle does change it.
  Can cancer be prevented? Many people believe that getting cancer is purely down to genes, fate or bad luck. But through scientific research, we know that our risk actually depends on a combination of our genes, our environment and aspects of our lives, many of which we can control. Cancer is caused by damage to our DNA, the chemical instructions that tell our cells what to do. Things in our environment, such as UV rays, or our lifestyle, such as the cancer-causing chemicals in tobacco, can damage our DNA. This damage builds up over time. If a cell develops too much damage to its DNA it can start to multiply out of control – this is how cancer starts. Find out more about what cancer is and how it grows. Family history and inherited genes Some people inherit damaged DNA from their parents, which can give them a higher risk of certain cancers. For example the BRCA genes are linked with breast, ovarian, prostate and other cancers. But the proportion of cancers caused by inherited faulty genes is small. Read more about inherited genes and cancer. How many cancers could be prevented? In the UK, more than 1 in 2 people will develop cancer at some point in their lives. Every year, more than 331,000 people are diagnosed with the disease. But experts estimate that more than 4 in 10 cancer cases could be prevented by lifestyle changes, such as: - not smoking - keeping a healthy bodyweight - cutting back on alcohol - eating a healthy, balanced diet - keeping active - avoiding certain infections (such as HPV) - enjoying the sun safely - occupation (avoiding cancer risks in the workplace) Surveys of the population have shown that people aren’t necessarily aware that all of these things are linked to cancer. For example, the Cancer Research UK funded Perceptions of Risk Survey in 2008 found that only 3% of the people polled knew that being overweight or obese could increase their risk of cancer.

 Reading 5: Can cancer be prevented? - A lifestyle does change it. Need some inspiration? Jeff, Mark, Maria and Emilie have all made changes towards a healthier lifestyle. Watch them explain what inspired them to make a change, how they did it and the way they feel about their lifestyles now Find Jeff, Maria, Emilie and Mark's full stories on our smoking, alcohol and obesity pages. Making lifestyle changes can be difficult, but there are so many benefits. Try to find tricks that make it easier to get into healthy habits, such as being active with a friend, keeping track of what you eat or drink, or letting your friends and family know about what you're doing. You can read our tips and advice for making healthier choices in different areas of your lifestyle in this section. And there are lots of other sources of information and support, such as the Change 4 Life website (link is external) or your GP or pharmacist. Is prevention a guarantee? Preventing cancer doesn’t work in the same way as preventing infectious diseases with vaccines. ‘Healthy living’ is not a cast-iron guarantee against cancer. But it stacks the odds in your favour, by reducing the risk of developing the disease. For example, we know that it’s possible for a heavy smoker to live a cancer-free life, while someone who never touches cigarettes could develop lung cancer. But lots of large long-term studies clearly show that people who have never smoked are far less likely to develop or die from cancer than smokers. In the same way, careful drivers cannot guarantee that they will never get into an accident due to events beyond their control, but they are much less likely to do so than reckless ones. Can lifestyle changes really make a difference? Yes, and not just for cancer. In 2008, a large UK study worked out how a combination of four healthy behaviours would affect your health. These were: not smoking; keeping active; moderating how much alcohol you drink; and eating five daily portions of fruit and vegetables. People who ticked all four healthy boxes gained an average of 14 years of life compared to people who did not do any of them. By the end of the study, they were less likely to have died from any cause. 

Unit10:Dementia

Reading1
 Eighty countries adopt call to action at first UN conference on dementia. 17 March 2015 – A two-day ministerial conference on dementia hosted by the United Nations World Health Organization (WHO) ended in Geneva today with 80 countries calling for action to address “a tidal wave” of new cases of the disease projected to cost the world $1.2 trillion by 2050. “You are starting a very important movement,” WHO’s Director-General, Dr. Margaret Chan, told a packed room of more than 400 delegates following the adoption of the Call for Action. Saying it is “one of the major health challenges for our generation,” the Call for Action noted that dementia currently affects more than 47 million people worldwide, with more than 75 million people estimated to be living with dementia by 2030. The number is expected to triple by 2050. Dr. Chan said the cost of dementia can bankrupt health systems “even in the richest countries,” referring to the worldwide cost of caring for patients with dementia climbing from some $607 billion in 2010 to an estimated $1.2 trillion in 2050. “There is a tidal wave of dementia coming our way worldwide,” she stated. “We need to see greater investments in research to develop a cure, but also to improve the quality of life of people living with dementia and the support given to their caregivers.” She welcomed the announcement by the United Kingdom that more than $100 million will be invested in a pioneering new global Dementia Discovery Fund. WHO said major pharmaceutical companies have committed in principle to investing in promising research efforts for dementia through the “innovative mechanism” that could bring about a breakthrough in treatment. Eighty countries joined the two-day conference with experts from the research, clinical and advocacy communities discussing how, collectively, they could move forward action on dementia at the global level. WHO said it committed to leading and coordinating efforts on dementia. It also pledged to establish a Global Dementia Observatory that will monitor disease prevalence and dementia care resources in Member States and track the establishment of national dementia policies and plans. The agency said there was clear consensus on the need for coordinated efforts to track evolution of the disease burden, create policies to address the impact of dementia, and conduct research for treatment and improved, cost-effective care. “We have been running behind the curve with dementia for a long time,” said Dr. Chan, “but several recent events tell us that we are catching up. We must weave these multiple new initiatives into a comprehensive plan that can work in all countries. Government commitment will be key”


Reading2
 30 years of Alzheimer's Disease International 1984-2014 In 1984, a small band of pioneers and experts came together with one dream in their minds: “a better life for people with dementia and their carers”. 30 years later, the vision is unchanged and the dedication unwavering. Alzheimer’s Disease International (ADI) has grown from 4 members to be the worldwide federation of more than 80 Alzheimer associations, becoming the global voice on dementia. ADI and its member organisations have campaigned to help people live well with dementia. Three decades on, dementia remains one of the most significant health crises of the 21st century. In response to this, ADI has launched major advocacy and awareness campaigns such as World Alzheimer’s Month, while over 100 countries have taken part in ADI’s Alzheimer University, a vital training programme for our members which supports both established and emerging national associations. Since 2009, ADI has also published annual World Alzheimer Reports, the first comprehensive global reviews on dementia. These reports have made key recommendations that continue to provide a global framework for international action on dementia. Global Solutions Alzheimer's Disease International (ADI) believes that the key to winning the fight against dementia lies in a unique combination of Global Solutions and local knowledge. As such, it works locally, by empowering Alzheimer associations to promote and offer care and support for people with dementia and their carers, while working globally to focus attention on dementia. Our board is composed of people from around the world, and our staff team is based in London. ADI is the international federation of Alzheimer associations around the world, in official relations with the World Health Organization. Each member is the Alzheimer association in their country who support people with dementia and their families. ADI's vision is an improved quality of life for people with dementia and their families throughout the world. ADI runs the Alzheimer University, a series of practical workshops aimed at helping the staff and volunteers of Alzheimer associations build and strengthen their organisations. ADI holds an annual international conference which is the longest-running international conference on dementia. The conference is a unique multi-disciplinary event which unites people with an interest in dementia from around the world. World Alzheimer's Month, celebrated each September with World Alzheimer's Day on September 21, is an opportunity to raise global awareness about dementia and its impact on families and the important work of our members throughout the world.


Reading3
 The Global Impact of Dementia: An Analysis of prevalence, incidence, cost and trends Background The World Alzheimer Report 2015 updates our estimates of the global prevalence, incidence and costs of dementia, based on systematic reviews. The report also includes a review of the evidence for and against trends in the prevalence and incidence of dementia. There are almost 900 million people aged 60 years and over living worldwide. Between 2015 and 2050, the number of older people living in high income countries is forecast to increase by 56%, compared with 138% in upper middle income countries, 185% in lower middle income countries, and by 239% low income countries. Rising life expectancy is contributing to rapid increases in numbers, and is associated with increased prevalence of chronic diseases like dementia.
 We estimate that 46.8 million people worldwide are living with dementia in 2015. This number will almost double every 20 years, reaching 74.7 million in 2030 and 131.5 million in 2050. These new estimates are 12-13% higher than those made for the World Alzheimer Report 2009. Our regional estimates of dementia prevalence in people aged 60 years and over range from 4.6% in Central Europe to 8.7% in North Africa and the Middle East, though all other regional estimates fall between 5.6% and 7.6%. When compared to our 2009 estimates, estimated prevalence is higher in East Asia and Africa. 58% of all people with dementia live in countries currently classified by the World Bank as low or middle income countries. This proportion is estimated to increase to 63% in 2030 and 68% in 2050.

Reading 4: World Alzheimer Report 2015 - Summary (cont.). The global incidence of dementia For 2015, we estimate over 9.9 million new cases of dementia each year worldwide, implying one new case every 3.2 seconds. This new estimate is almost 30% higher than the annual number of new cases we estimated for 2010 in the 2012 World Health Organization report, ‘Dementia: a public health priority’. The regional distribution of new dementia cases is 4.9 million (49% of the total) in Asia, 2.5 million (25%) in Europe, 1.7 million (18%) in the Americas, and 0.8 million (8%) in Africa. Compared to our 2012 estimates, these values represent an increased proportion of new cases arising in Asia, the Americas and Africa, while the proportion arising in Europe has fallen. The incidence of dementia increases exponentially with increasing age, doubling with every 6.3 year increase in age, from 3.9 per 1000 person-years at age 60-64, to 104.8 per 1000 person-years at age 90+. The worldwide costs of dementia The estimates of global societal economic costs of dementia provided in our 2015 report have been generated using the same general approach as for the World Alzheimer Report 2010. For each country, we estimated cost per person, which is then multiplied by the number of people estimated to be living with dementia in that country. Per person costs are divided into three cost sub-categories: direct medical costs, direct social care costs (paid and professional home care, and residential and nursing home care) and costs of informal (unpaid) care. The global costs of dementia have increased from US$ 604 billion in 2010 to US$ 818 billion in 2015, an increase of 35.4%. Our current estimate of US$ 818 billion represents 1.09% of global GDP, an increase from our 2010 estimate of 1.01%. Excluding informal care costs, total direct costs account for 0.65% of global GDP. Cost estimates have increased for all world regions, with the greatest relative increases occurring in the African and in East Asia regions (largely due to higher prevalence estimates for these regions). Distribution of costs between the three sub-categories (direct medical, social care, and informal care) has not changed substantially. Direct medical care costs account for roughly 20% of global dementia costs, while direct social sector costs and informal care costs each account for roughly 40%. The relative contribution of informal care is greatest in the African regions and lowest in North America, Western Europe and some South American regions, while the reverse is true for social sector costs. Reading 5: World Alzheimer Report 2015 - Summary (cont.). Trends in prevalence and incidence Almost all current projections of the coming dementia epidemic assume that age- and gender-specific prevalence of dementia will not vary over time, and that population ageing alone drives the projected increases. The prevalence of any condition is a product of its incidence and the average duration of the disease episode. Changes in either or both of these indicators could lead to changes in age-specific prevalence. One should not expect that secular trends will be the same across all world regions, or even among different population subgroups within one country. Experience with changing rates of cardiovascular disease, obesity, diabetes and cancer shows this clearly. The considerable variability in secular trends for these chronic diseases reflect different degrees of progress in improving public health, and in improving access to health care and strengthening health systems and services to better detect, treat and control these conditions. Findings across the identified studies (mostly conducted in high income countries) are currently too inconsistent to reach firm and generalisable conclusions regarding underlying trends. Studies that use fixed methodology to estimate changes in dementia prevalence, incidence and mortality over time, in defined populations, are valuable and it is important that more are commissioned. Recommendations The report includes Alzheimer’s Disease International’s (ADI) recommendations, including; that dementia risk reduction should be an explicit priority in work led by the World Health Organization (WHO), with clear linked actions including targets and indicators; that research investment for dementia should be scaled up, proportionate to the societal cost of the disease; and that this investment should be balanced between prevention, treatment, care and cure. Epidemiological research is particularly sparse in Central Asia, Eastern Europe, Southern Latin America, and Eastern and Southern sub-Saharan Africa. ADI applauds the action taken by the G7 in launching a ‘Global Action Against Dementia’, and calls for this initiative to be continued with a broader agenda and wider representation from the countries and regions most affected by the ongoing dementia epidemic. ADI advocates for a transfer of political leadership to the G20 nations. ADI endorses the ‘call for action’ agreed at the WHO Ministerial Conference on Global Action Against Dementia (March 2015), which needs to be translated into operationalised plans with clear targets and deliverables at international and national level.